Diabetes -- Table of Contents (September 2008, 57 [9])

Banting Lecture:

Bringing Light to the Dark Side of Insulin: A Journey Across the Blood-Brain Barrier: Robert S. Sherwin
Diabetes 2008 57: 2259 -2268. [Extract] [Full Text] [PDF]

Commentary:

Revascularization of Transplanted Islets: Can It Be Improved?: Marcela Brissova and Alvin C. Powers
Diabetes 2008 57: 2269 -2271. [Extract] [Full Text] [PDF]

Metabolism:

Pyruvate Dehydrogenase Kinase 4: Regulation by Thiazolidinediones and Implication in Glyceroneogenesis in Adipose Tissue: Thomas Cadoudal, Emilie Distel, Sylvie Durant, Françoise Fouque, Jean-Marc Blouin, Martine Collinet, Sylvie Bortoli, Claude Forest, and Chantal Benelli
Diabetes 2008 57: 2272 -2279. First published on June 2, 2008 as 10.2337/db08-0477 [Abstract] [Full Text] [PDF]

Gpr40 Is Expressed in Enteroendocrine Cells and Mediates Free Fatty Acid Stimulation of Incretin Secretion: Sara Edfalk, Pär Steneberg, and Helena Edlund
Diabetes 2008 57: 2280 -2287. First published on June 2, 2008 as 10.2337/db08-0307 [Abstract] [Full Text] [PDF]

Pioglitazone Decreases Fasting and Postprandial Endogenous Glucose Production in Proportion to Decrease in Hepatic Triglyceride Content: Balasubramanian Ravikumar, Jean Gerrard, Chiara Dalla Man, Michael J. Firbank, Annette Lane, Philip T. English, Claudio Cobelli, and Roy Taylor
Diabetes 2008 57: 2288 -2295. First published on June 5, 2008 as 10.2337/db07-1828 [Abstract] [Full Text] [PDF]

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1: A Link Between Insulin and Lipid Metabolism: Anthony M. DeAngelis, Garrett Heinrich, Tong Dai, Thomas A. Bowman, Payal R. Patel, Sang Jun Lee, Eun-Gyoung Hong, Dae Young Jung, Anke Assmann, Rohit N. Kulkarni, Jason K. Kim, and Sonia M. Najjar
Diabetes 2008 57: 2296 -2303. First published on June 10, 2008 as 10.2337/db08-0379 [Abstract] [Full Text] [PDF]

Intracerebroventricular Administration of Neuropeptide Y Induces Hepatic Insulin Resistance via Sympathetic Innervation: Anita M. van den Hoek, Caroline van Heijningen, Janny P. Schröder-van der Elst, D. Margriet Ouwens, Louis M. Havekes, Johannes A. Romijn, Andries Kalsbeek, and Hanno Pijl
Diabetes 2008 57: 2304 -2310. First published on June 10, 2008 as 10.2337/db07-1658 [Abstract] [Full Text] [PDF]

Deletion of Cd39/Entpd1 Results in Hepatic Insulin Resistance: Keiichi Enjyoji, Ko Kotani, Chandrashekar Thukral, Benjamin Blumel, Xiaofeng Sun, Yan Wu, Masato Imai, David Friedman, Eva Csizmadia, Wissam Bleibel, Barbara B. Kahn, and Simon C. Robson
Diabetes 2008 57: 2311 -2320. First published on June 20, 2008 as 10.2337/db07-1265 [Abstract] [Full Text] [PDF]

Signal Transduction:

Metabolically Favorable Remodeling of Human Adipose Tissue by Human Adenovirus Type 36: Pamela M. Rogers, Nazar Mashtalir, Miloni A. Rathod, Olga Dubuisson, Zhong Wang, Kumar Dasuri, Scott Babin, Alok Gupta, Nathan Markward, William T. Cefalu, and Nikhil V. Dhurandhar
Diabetes 2008 57: 2321 -2331. First published on July 3, 2008 as 10.2337/db07-1311 [Abstract] [Full Text] [PDF] Online-Only Appendix

Obesity Studies:

Cholinergic Regulation of Ghrelin and Peptide YY Release May Be Impaired in Obesity: Christina Maier, Michaela Riedl, Greisa Vila, Peter Nowotny, Michael Wolzt, Martin Clodi, Bernhard Ludvik, and Anton Luger
Diabetes 2008 57: 2332 -2340. First published on June 20, 2008 as 10.2337/db07-0758 [Abstract] [Full Text] [PDF]

Immunology and Transplantation:

Rapamycin Monotherapy in Patients With Type 1 Diabetes Modifies CD4⁺CD25⁺FOXP3⁺ Regulatory T-Cells: Paolo Monti, Miriam Scirpoli, Paola Maffi, Lorenzo Piemonti, Antonio Secchi, Ezio Bonifacio, Maria-Grazia Roncarolo, and Manuela Battaglia
Diabetes 2008 57: 2341 -2347. First published on June 16, 2008 as 10.2337/db08-0138 [Abstract] [Full Text] [PDF]

Impact of Diabetes Susceptibility Loci on Progression From Pre-Diabetes to Diabetes in At-Risk Individuals of the Diabetes Prevention Trial–Type 1 (DPT-1): Vincent Butty, Christopher Campbell, Diane Mathis, Christophe Benoist, and the DPT-1 Study Group
Diabetes 2008 57: 2348 -2359. First published on June 12, 2008 as 10.2337/db07-1736 [Abstract] [Full Text] [PDF] Online-Only Appendix

Plasmacytoid Precursor Dendritic Cells From NOD Mice Exhibit Impaired Function: Are They a Component of Diabetes Pathogenesis?: Yiming Huang, Isabelle J. Fugier-Vivier, Thomas Miller, Mary J. Elliott, Hong Xu, Larry D. Bozulic, Paula M. Chilton, and Suzanne T. Ildstad
Diabetes 2008 57: 2360 -2370. First published on June 20, 2008 as 10.2337/db08-0356 [Abstract] [Full Text] [PDF] Online-Only Appendix

Islet Studies:

Exendin-4 Stimulation of Cyclin A2 in β-Cell Proliferation: Woo-Jin Song, Weston E. Schreiber, Enhong Zhong, Fei-Fei Liu, Benjamin D. Kornfeld, Fredric E. Wondisford, and Mehboob A. Hussain
Diabetes 2008 57: 2371 -2381. First published on June 10, 2008 as 10.2337/db07-1541 [Abstract] [Full Text] [PDF] Online-Only Appendix

Palmitate Impairs and Eicosapentaenoate Restores Insulin Secretion Through Regulation of SREBP-1c in Pancreatic Islets: Toyonori Kato, Hitoshi Shimano, Takashi Yamamoto, Mayumi Ishikawa, Shin Kumadaki, Takashi Matsuzaka, Yoshimi Nakagawa, Naoya Yahagi, Masanori Nakakuki, Alyssa H. Hasty, Yoshinori Takeuchi, Kazuto Kobayashi, Akimitsu Takahashi, Shigeru Yatoh, Hiroaki Suzuki, Hirohito Sone, and Nobuhiro Yamada
Diabetes 2008 57: 2382 -2392. First published on May 5, 2008 as 10.2337/db06-1806 [Abstract] [Full Text] [PDF] Online-Only Appendix

Formation of Composite Endothelial Cell–Mesenchymal Stem Cell Islets: A Novel Approach to Promote Islet Revascularization: Ulrika Johansson, Ida Rasmusson, Simone P. Niclou, Naomi Forslund, Linda Gustavsson, Bo Nilsson, Olle Korsgren, and Peetra U. Magnusson
Diabetes 2008 57: 2393 -2401. First published on June 2, 2008 as 10.2337/db07-0981 [Abstract] [Full Text] [PDF]

Switching-On Survival and Repair Response Programs in Islet Transplants by Bone Marrow–Derived Vasculogenic Cells: Robyn Miller, Vincenzo Cirulli, Giuseppe R. Diaferia, Stefania Ninniri, Gary Hardiman, Bruce E. Torbett, Robert Benezra, and Laura Crisa
Diabetes 2008 57: 2402 -2412. First published on June 2, 2008 as 10.2337/db08-0244 [Abstract] [Full Text] [PDF] Online-Only Appendix

HES-1 Is Involved in Adaptation of Adult Human β-Cells to Proliferation In Vitro: Yael Bar, Holger A. Russ, Sarah Knoller, Limor Ouziel-Yahalom, and Shimon Efrat
Diabetes 2008 57: 2413 -2420. First published on July 3, 2008 as 10.2337/db07-1323 [Abstract] [Full Text] [PDF] Online-Only Appendix

Reduction of Ptf1a Gene Dosage Causes Pancreatic Hypoplasia and Diabetes in Mice: Akihisa Fukuda, Yoshiya Kawaguchi, Kenichiro Furuyama, Sota Kodama, Masashi Horiguchi, Takeshi Kuhara, Michiya Kawaguchi, Mami Terao, Ryuichiro Doi, Christopher V.E. Wright, Mikio Hoshino, Tsutomu Chiba, and Shinji Uemoto
Diabetes 2008 57: 2421 -2431. First published on June 30, 2008 as 10.2337/db07-1558 [Abstract] [Full Text] [PDF]

The Fatty Acid Receptor GPR40 Plays a Role in Insulin Secretion In Vivo After High-Fat Feeding: Melkam Kebede, Thierry Alquier, Martin G. Latour, Meriem Semache, Caroline Tremblay, and Vincent Poitout
Diabetes 2008 57: 2432 -2437. First published on June 16, 2008 as 10.2337/db08-0553 [Abstract] [Full Text] [PDF] Online-Only Appendix Revised Figure 2

Pathophysiology:

Increase in Endoplasmic Reticulum Stress–Related Proteins and Genes in Adipose Tissue of Obese, Insulin-Resistant Individuals: Guenther Boden, Xunbao Duan, Carol Homko, Ezequiel J. Molina, WeiWei Song, Oscar Perez, Peter Cheung, and Salim Merali
Diabetes 2008 57: 2438 -2444. First published on June 20, 2008 as 10.2337/db08-0604 [Abstract] [Full Text] [PDF]

Evidence for Interindividual Heterogeneity in the Glucose Gradient Across the Human Red Blood Cell Membrane and Its Relationship to Hemoglobin Glycation: Paramjit K. Khera, Clinton H. Joiner, Anthony Carruthers, Christopher J. Lindsell, Eric P. Smith, Robert S. Franco, Yancey R. Holmes, and Robert M. Cohen
Diabetes 2008 57: 2445 -2452. First published on June 30, 2008 as 10.2337/db07-1820 [Abstract] [Full Text] [PDF]

Effects of a Selective Serotonin Reuptake Inhibitor, Fluoxetine, on Counterregulatory Responses to Hypoglycemia in Healthy Individuals: Vanessa J. Briscoe, Andrew C. Ertl, Donna B. Tate, Sheila Dawling, and Stephen N. Davis
Diabetes 2008 57: 2453 -2460. First published on June 20, 2008 as 10.2337/db08-0236 [Abstract] [Full Text] [PDF]

Complications:

Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes: Aino Soro-Paavonen, Anna M.D. Watson, Jiaze Li, Karri Paavonen, Audrey Koitka, Anna C. Calkin, David Barit, Melinda T. Coughlan, Brian G. Drew, Graeme I. Lancaster, Merlin Thomas, Josephine M. Forbes, Peter P. Nawroth, Angelika Bierhaus, Mark E. Cooper, and Karin A. Jandeleit-Dahm
Diabetes 2008 57: 2461 -2469. First published on May 28, 2008 as 10.2337/db07-1808 [Abstract] [Full Text] [PDF] Online-Only Appendix

Differential Roles of Cardiomyocyte and Macrophage Peroxisome Proliferator–Activated Receptor ${gamma}$ in Cardiac Fibrosis: Evren Caglayan, Bradley Stauber, Alan R. Collins, Christopher J. Lyon, Fen Yin, Joey Liu, Stephan Rosenkranz, Erland Erdmann, Leif E. Peterson, Robert S. Ross, Rajendra K. Tangirala, and Willa A. Hsueh
Diabetes 2008 57: 2470 -2479. First published on May 28, 2008 as 10.2337/db07-0924 [Abstract] [Full Text] [PDF] Online-Only Appendix

Metabolic Phenotypes, Vascular Complications, and Premature Deaths in a Population of 4,197 Patients With Type 1 Diabetes: Ville-Petteri Mäkinen, Carol Forsblom, Lena M. Thorn, Johan Wadén, Daniel Gordin, Outi Heikkilä, Kustaa Hietala, Laura Kyllönen, Janne Kytö, Milla Rosengård-Bärlund, Markku Saraheimo, Nina Tolonen, Maija Parkkonen, Kimmo Kaski, Mika Ala-Korpela, Per-Henrik Groop on behalf of the FinnDiane Study Group
Diabetes 2008 57: 2480 -2487. First published on June 10, 2008 as 10.2337/db08-0332 [Abstract] [Full Text] [PDF] Online-Only Appendix

Carbon Monoxide and Nitric Oxide Mediate Cytoskeletal Reorganization in Microvascular Cells via Vasodilator-Stimulated Phosphoprotein Phosphorylation: Evidence for Blunted Responsiveness in Diabetes: Sergio Li Calzi, Daniel L. Purich, Kyung Hee Chang, Aqeela Afzal, Takahiko Nakagawa, Julia V. Busik, Anupam Agarwal, Mark S. Segal, and Maria B. Grant
Diabetes 2008 57: 2488 -2494. First published on June 16, 2008 as 10.2337/db08-0381 [Abstract] [Full Text] [PDF]

Pericyte Migration: A Novel Mechanism of Pericyte Loss in Experimental Diabetic Retinopathy: Frederick Pfister, Yuxi Feng, Franziska vom Hagen, Sigrid Hoffmann, Grietje Molema, Jan-Luuk Hillebrands, Moshe Shani, Urban Deutsch, and Hans-Peter Hammes
Diabetes 2008 57: 2495 -2502. First published on June 16, 2008 as 10.2337/db08-0325 [Abstract] [Full Text] [PDF]

Genetics:

Extension of Type 2 Diabetes Genome-Wide Association Scan Results in the Diabetes Prevention Program: Allan F. Moore, Kathleen A. Jablonski, Jarred B. McAteer, Richa Saxena, Toni I. Pollin, Paul W. Franks, Robert L. Hanson, Alan R. Shuldiner, William C. Knowler, David Altshuler, Jose C. Florez for the Diabetes Prevention Program Research Group
Diabetes 2008 57: 2503 -2510. First published on June 10, 2008 as 10.2337/db08-0284 [Abstract] [Full Text] [PDF] Online-Only Appendix

Prevalence of Melanocortin-4 Receptor Deficiency in Europeans and Their Age-Dependent Penetrance in Multigenerational Pedigrees: Fanny Stutzmann, Karen Tan, Vincent Vatin, Christian Dina, Béatrice Jouret, Jean Tichet, Beverley Balkau, Natascha Potoczna, Fritz Horber, Stephen O'Rahilly, I. Sadaf Farooqi, Philippe Froguel, and David Meyre
Diabetes 2008 57: 2511 -2518. First published on June 16, 2008 as 10.2337/db08-0153 [Abstract] [Full Text] [PDF] Online-Only Appendix

High-Density Single Nucleotide Polymorphism Genome-Wide Linkage Scan for Susceptibility Genes for Diabetic Nephropathy in Type 1 Diabetes: Discordant Sibpair Approach: John J. Rogus, G. David Poznik, Marcus G. Pezzolesi, Adam M. Smiles, Jonathon Dunn, William Walker, Krzysztof Wanic, Dariusz Moczulski, Luis Canani, Shinichi Araki, Yuichiro Makita, James H. Warram, and Andrzej S. Krolewski
Diabetes 2008 57: 2519 -2526. First published on June 16, 2008 as 10.2337/db07-1086 [Abstract] [Full Text] [PDF] Online-Only Appendix

Evaluating the Role of LPIN1 Variation in Insulin Resistance, Body Weight, and Human Lipodystrophy in U.K. Populations: Katherine A. Fawcett, Neil Grimsey, Ruth J.F. Loos, Eleanor Wheeler, Allan Daly, Maria Soos, Robert Semple, Holly Syddall, Cyrus Cooper, Symeon Siniossoglou, Stephen O'Rahilly, Nicholas J. Wareham, and Inês Barroso
Diabetes 2008 57: 2527 -2533. First published on June 30, 2008 as 10.2337/db08-0422 [Abstract] [Full Text] [PDF] Online-Only Appendix

Association Testing of Novel Type 2 Diabetes Risk Alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 Loci With Insulin Release, Insulin Sensitivity, and Obesity in a Population-Based Sample of 4,516 Glucose-Tolerant Middle-Aged Danes: Niels Grarup, Gitte Andersen, Nikolaj T. Krarup, Anders Albrechtsen, Ole Schmitz, Torben Jørgensen, Knut Borch-Johnsen, Torben Hansen, and Oluf Pedersen
Diabetes 2008 57: 2534 -2540. First published on June 20, 2008 as 10.2337/db08-0436 [Abstract] [Full Text] [PDF] Online-Only Appendix

Is the Presence of Retinopathy of Practical Value in Defining Cases of Diabetic Nephropathy in Genetic Association Studies?: The Experience With the ACE Insertion/Deletion Polymorphism in 53 Studies Comprising 17,791 Subjects: Daniel P.K. Ng, Bee-Choo Tai, and Xiu-Li Lim
Diabetes 2008 57: 2541 -2546. First published on June 3, 2008 as 10.2337/db08-0581 [Abstract] [Full Text] [PDF] Online-Only Appendix

Exclusion of Polymorphisms in Carnosinase Genes (CNDP1 and CNDP2) as a Cause of Diabetic Nephropathy in Type 1 Diabetes: Results of Large Case-Control and Follow-Up Studies: Krzysztof Wanic, Grzegorz Placha, Jonathon Dunn, Adam Smiles, James H. Warram, and Andrzej S. Krolewski
Diabetes 2008 57: 2547 -2551. [Abstract] [Full Text] [PDF]

Errata:

Errata: Diabetes 2008 57: 2552 . [Extract] [Full Text] [PDF]

Errata: Diabetes 2008 57: 2552 . [Extract] [Full Text] [PDF]